J Gynecol Oncol | Volume 7, Issue 1 | Case Report | Open Access
Rothnie K*, Panella L, Goltzman S, Bhana D, Danziger M, Frimer M, Goldberg GL and
Whyte J
Department of Gynecologic Oncology, Northwell Health Cancer Institute, United States
Department of Obstetrics and Gynecology, Long Island Jewish Hospital, United States
*Correspondance to: Kersten Rothnie
Fulltext PDFObjectives: We report two cases with late-presentation of Port site metastases (PSMs) in early-stage
low-risk endometrioid endometrial adenocarcinoma.
Methods: A retrospective review of two patients with FIGO 2009 stage IA grade 1 endometrioid
endometrial cancer who developed PSM from 2011 to 2025 at the Northwell Health and Northwell
Cancer Institute. Treatment and outcome data were collected.
Results: Median age at time of recurrence was 72.6 years. Both patients had FIGO 2009 stage
IA grade 1 endometrioid endometrial adenocarcinoma, however one patient had concomitant
stage IC grade 2 endometrioid adenocarcinoma of the right fallopian tube and received adjuvant
chemotherapy. The median interval from initial endometrial cancer diagnosis to development of
the PSM was 10.8 years (range, 8.9–12.8 years), with the PSM being consistent with their original
endometrial cancer pathology and surgical resection being performed in both patients. At a median
follow-up of 14.5 years, both patients are alive and disease-free.
Conclusions: Late presentation of PSMs following early-stage low-risk endometrioid endometrial
cancer is a rare entity. The long disease-free intervals between initial diagnosis and port site
recurrence supports the use of aggressive management to achieve favourable clinical outcomes.
Minimally invasive surgery; Gynecology; Pathology
Rothnie K, Panella L, Goltzman S, Bhana D, Danziger M, Frimer M, et al. Late Port Site Metastases After Minimally Invasive Surgery for Early- Stage Endometrial Carcinoma: A Case Report. J Gynecol Oncol. 2026; 7(1): 1086..