J Respir Med Lung Dis | Volume 9, Issue 1 | Research Article | Open Access
Anand Kumar, Amaan Latif, Abhinav Kumar, Sanjay Verma, Akhil Tiwari and Gaurav Srivastava
Department of Respiratory Medicine, GSVM Medical College, Kanpur, India
Department of Tuberculosis and Respiratory Diseases, JLN Medical College and Hospital, Aligarh Muslim
University Aligarh, India
Department of Respiratory Medicine, KGMU Lucknow, India
*Correspondance to: Anand Kumar
Fulltext PDFBackground: Lung cancer remains the most common neoplasm worldwide, contributing significantly to cancer-related mortality. Due to late-stage presentation in many patients, early and accurate diagnostic methods are critical. Flexible bronchoscopy, employing various sampling techniques, plays a crucial role in the diagnostic process. Methods: An interventional cross-sectional study was conducted at the Department of Respiratory Medicine, GSVM Medical College, Kanpur, between January 2021 and December 2023. Patients with a suspected lung mass underwent diagnostic bronchoscopy. Procedures included bronchial wash, brush cytology, biopsy, and Transbronchial Needle Aspiration (TBNA). Diagnostic yields were evaluated for individual procedures and various combinations. Results: A total of 308 patients were analyzed, with a male-to-female ratio of 3:1. The diagnostic yields for individual procedures were: BAL fluid cytology (44.4%), bronchial brush cytology (47.6%), biopsy (71.7%), and TBNA cytology (78.4%). The use of combined sampling techniques, particularly BAL with biopsy and brush/TBNA, significantly enhanced diagnostic yield, achieving up to 94.1%. Conclusion: Bronchoscopy remains an essential tool for the diagnosis of lung cancer. Combining multiple bronchoscopic sampling techniques markedly improves diagnostic efficacy and should be considered to optimize outcomes.
Bronchoscopy; Diagnostic yield; Lung cancer; Bronchial wash; Brush cytology; TBNA; Biopsy.
Kumar A, Latif A, Kumar A, Verma S, Tiwari A, Srivastava G. Diagnostic Yield of Conventional Bronchoscopic Techniques: A Study on Different Sampling Combinations in Suspected Lung Cancer. J Respir Med Lung Dis. 2025; 9(1): 1065.